Coenzyme Q10

Also known as
CoQ10, Ubiquinone, Ubiquinol

 

What Is CoQ10 and Why Is It Important?

Coenzyme Q10 (CoQ10) is a molecule produced in the body. It is an antioxidant that is necessary for cells to function properly. Cells use CoQ10 to make the energy they need to grow and stay healthy. Levels of CoQ10 decrease as you age.

Several diseases are associated with low levels of CoQ10, including fibromyalgia and the aftermath of a heart attack, known as post-myocardial infarction. Depression, Prader-Willi syndrome, male infertility, Peyronie’s disease, migraines, and Parkinson’s also cause a CoQ10 deficiency. Supplementation of CoQ10 is recommended to anyone with the listed diseases, but particularly for heart attack victims and people suffering from fibromyalgia.

Several pharmaceuticals are known to deplete CoQ10 levels (statin drugs are a good example). Doctor-supervised supplementation can reduce this effect.

 

Benefits

  • Reduce free radical damage, CoQ10 has been found to inhibit lipid peroxidation and protect cell membrane and DNA from the oxidative damage which directly contribute to nearly all age-related diseases (heart disease, cancer, diabetes, neurological disease, etc.).
  • Increase blood flow in metabolic conditions characterized by both insufficient blood flow and an excess of oxidative stress.
  • CoQ10 appears to be quite strongly effective for reducing symptoms of fibromyalgia.
  • Improve physical performance and aid exercise capacity especially in persons after myocardial infarction.

 

Safety

  • CoQ10 has mild side effects and is generally well tolerated.
  • The most common side effects of CoQ10 include insomnia, increased liver enzymes, rashes, nausea, upper abdominal pain, dizziness, sensitivity to light, irritability, headaches, heartburn, and fatigue.
  • CoQ10 may make warfarin, an anticoagulant (blood thinner), less effective.
  • CoQ10 should not be used by women who are pregnant or breastfeeding.

 

Reference

  1. National Center for Complementary and Integrative Health. Coenzyme Q10 (CoQ10): In Depth. National Institutes of Health, U.S. Department of Health and Human Services Web Site. Accessed at https://nccih.nih.gov/health/supplements/coq10 on July 03, 2018.
  2. Kamal Patel. Coenzyme Q10. Examine.com Web Site. Accessed at https://examine.com/supplements/coenzyme-q10/ on July 03, 2018.